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Article of the month
Getting Younger From The Inside Out
Thousands of years ago Herodotus the 5th century BC Greek historian wrote
stories of a mythical fountain that bestowed eternal youth. In the 16 century
Juan Ponce de Leon searched for such a fountain in what is now Florida.
Today some scientists believe they may have found a type of fountain of
youth if you will, within our own bodies. This source of eternal youthfulness
may be attributed to a repetitive DNA sequence that caps our chromosomes
known as telomeres.
Telomeres work like the plastic caps on our shoe strings in this case
protecting the strands of coded DNA. Every time the cell replicates the
telomere ends get a little shorter thus limiting the amount of times the cell can
reproduce before dying (Hayflick Limit). The reason for this is to prevent
mutated or dysfunctional cells from passing on errant traits. By studying
cancer cells it has been found that telomeres can be lengthened keeping the
cells alive (immortalizing) and replicating. The process occurs one of two ways
by the cell releasing an enzyme (telomerase) or through a function of
recombination (ALT).
Scientists now largely believe that if a healthy cell has longer telomeres it will
live longer and healthier and therefore pass on more healthy versions of itself.
In effect, if the cell looks and functions younger then so, too shall the entire
organism.
A recent study at King’s College in London examined the telomeres of
thousands of subjects including identical twins over a 10 year period to see
what effect exercise may have at the cellular level. Adjusting for things like
smoking, BMI, and social status they found that those who exercised
vigorously for 3 hours a week had longer telomeres equivalent to cells 9 years
younger. Even those who exercise about 90 minutes a week saw a 4 year
improvement.
A follow on German study found runners had about 30% longer telomeres
than their comparable sedentary counterparts. Couple this to two other recent
studies showing that both omega 3 fatty acids and supplements of vitamin D
also lengthen telomeres and we may very well be dipping our toes into the
fountain after all.
Article of the month
Getting Younger From The Inside Out
Thousands of years ago Herodotus the 5th century BC Greek historian wrote
stories of a mythical fountain that bestowed eternal youth. In the 16 century
Juan Ponce de Leon searched for such a fountain in what is now Florida.
Today some scientists believe they may have found a type of fountain of
youth if you will, within our own bodies. This source of eternal youthfulness
may be attributed to a repetitive DNA sequence that caps our chromosomes
known as telomeres.
Telomeres work like the plastic caps on our shoe strings in this case
protecting the strands of coded DNA. Every time the cell replicates the
telomere ends get a little shorter thus limiting the amount of times the cell can
reproduce before dying (Hayflick Limit). The reason for this is to prevent
mutated or dysfunctional cells from passing on errant traits. By studying
cancer cells it has been found that telomeres can be lengthened keeping the
cells alive (immortalizing) and replicating. The process occurs one of two ways
by the cell releasing an enzyme (telomerase) or through a function of
recombination (ALT).
Scientists now largely believe that if a healthy cell has longer telomeres it will
live longer and healthier and therefore pass on more healthy versions of itself.
In effect, if the cell looks and functions younger then so, too shall the entire
organism.
A recent study at King’s College in London examined the telomeres of
thousands of subjects including identical twins over a 10 year period to see
what effect exercise may have at the cellular level. Adjusting for things like
smoking, BMI, and social status they found that those who exercised
vigorously for 3 hours a week had longer telomeres equivalent to cells 9 years
younger. Even those who exercise about 90 minutes a week saw a 4 year
improvement.
A follow on German study found runners had about 30% longer telomeres
than their comparable sedentary counterparts. Couple this to two other recent
studies showing that both omega 3 fatty acids and supplements of vitamin D
also lengthen telomeres and we may very well be dipping our toes into the
fountain after all.
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